Showing 1,012 registered airlines with a combined fleet of 8,880 airframes.
| Airline Name | ICAO / IATA | Fleet Size |
|---|---|---|
| Shuttle America | TCF / S5 | 3 |
| Sierra Express | SIE | 0 |
| Sierra Expressway Airlines | SRX | 0 |
| Sierra Pacific Airlines | SPA | 2 |
| Silk Avia LLC | USA / US | 0 |
| Silvair | IJS | 0 |
| Silverhawk Aviation | SLH | 15 |
| Sioux Falls Aviation | DKT | 1 |
| Skagway Air Service | SGY / N5 | 0 |
| Sky Bus | FLH | 0 |